2-Phenyl-L-glycinamide hydrochloride - Names and Identifiers
2-Phenyl-L-glycinamide hydrochloride - Physico-chemical Properties
Molecular Formula | C8H11ClN2O
|
Molar Mass | 186.64 |
Appearance | Solid |
Storage Condition | Sealed in dry,Room Temperature |
2-Phenyl-L-glycinamide hydrochloride - Introduction
H-PHG-NH2 HCL (H-PHG-NH2 HCl) is a pharmaceutical intermediate with the following properties:
1. Appearance: white crystalline powder;
2. Molecular formula: C8H11ClN2O;
3. Molecular weight: 184.64g/mol;
4. Melting Point: 146-148 C;
5. Solubility: Soluble in water and some organic solvents, such as methanol and ethanol.
H-PHG-NH2 HCL is mainly used for the synthesis of α-hydroxy amide compounds. It is widely used in the pharmaceutical industry to synthesize peptide drugs and bioactive molecules. In addition, it can also be used as a catalyst for other organic synthesis reactions.
The method of preparing H-PHG-NH2 HCL usually includes the following steps:
1. Synthesis of (S)-phenylalaninol;
2. (S)-2-amino-2-phenylacetamide is obtained by acidification, activation and condensation of (S)-phenylalaninol;
3. Finally, (S)-2-amino-2-phenylacetamide is reacted with hydrochloric acid to obtain H-PHG-NH2 HCL.
When using H-PHG-NH2 HCL, you need to pay attention to the following safety information:
1. Avoid direct contact with skin and eyes, such as contact should immediately rinse with water.
2. Operation should wear appropriate protective gloves and eye protection.
3. Follow Good Laboratory operating procedures and make ventilation facilities.
Please note that the above content is for reference only. The specific use should be operated according to the specific situation and experimental purpose, and follow the relevant safety operation procedures.
Last Update:2024-04-09 20:52:54